Kacper A. Walentynowicz, PhD
Research Associate | Cancer Biology & Genetics, MSKCC
Life Sciences Technology Innovation Fellow | Cornell SC Johnson College of Business
About Me
I'm a Research Associate with a strong background in Immuno-Oncology, currently based in New York City. My work focuses on understanding the tumor microenvironment of Glioblastoma (GBM), with a particular interest in the role of glioma-associated microglia and macrophages.
Using computational methods and animal models, I investigate the functional heterogeneity of immune cells within tumors and how they contribute to tumor progression and immune evasion. My goal is to identify new therapeutic targets and develop novel CAR-macrophage immunotherapies. I have received extensive training in novel sequencing methods, myeloid cell manipulations, computational analysis or large datasets, novel animal models of GBM, and advanced flow-cytometry analysis.
Professional Experience
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Research Associate, Sloan Kettering Institute, USCurrent
Developing novel CAR-macrophage immunotherapy and studying NF1 mutant gliomas. | Parada Lab
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Postdoctoral Fellow, Scripps Research, US
Investigating genetic alterations in GBM and their impact on tumor microenvironment. | Janiszewska Lab
Education
Life Science Entrepreneurship in Practice
Cornell SC Johnson College of Business, US
PhD, Marie Sklodowska-Curie Fellow
Nencki Institute, Warsaw, Poland
MSc, Molecular Medicine
The Sheffield University Medical School, UK
PDP in Cancer Informatics
Imperial College London, UK
BSc (Hons), Biomedical Science
University of Wolverhampton, UK
Research Interests
- Glioblastoma (GBM) tumor microenvironment
- Single-cell heterogeneity of cancer and immune cells
- Glioma-associated microglia and macrophages (GAMs)
- Molecular mechanisms of immune evasion in brain tumors
- Translational research for novel GBM therapies
Selected Publications
Single-cell heterogeneity of EGFR and CDK4 co-amplification is linked to immune infiltration in glioblastoma
Kacper A Walentynowicz, Dalit Engelhardt, et al.
Cell Reports, 2023 Mar 28;42(3):112235.
Single-cell RNA sequencing reveals functional heterogeneity of glioma-associated brain macrophages
Natalia Ochocka, Pawel Segit, Kacper A Walentynowicz, et. al.
Nature Communications, 2021 Feb 19;12(1):1111.
In Search for Reliable Markers of Glioma-Induced Polarization of Microglia
Kacper A Walentynowicz, Natalia Ochocka, et al.
Frontiers in Immunology, 2018 Jun 15;9:1329.
Immune microenvironment of gliomas
Anna Gieryng, Dominika Pszczolkowska, Kacper A Walentynowicz, et al.
Laboratory Investigation, 2017 May;97(5):498-518.
Google Scholar Statistics
Statistics last updated: Oct 6th, 2025
